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Expression of Fas Ligand and bcl-2 in Cervical Carcinoma and Their Prognostic Significance
American Journal of Clinical Pathology
A b s t r a c t Apoptosis-related factors are known to influence survival with many malignant tumors. We performed immunohistochemical analysis of Fas ligand (FasL) and bcl-2 in invasive cervical cancer to determine the association with prognosis. In 125 patients with cervical cancer, 93 cases (74.4%) were positive for FasL, and 94 cases (75.2%) were positive for bcl-2. When 101 cases, clinical stages I through IV, were analyzed by univariate analysis, negative bcl-2 (P = .035) and combineddoi:10.1309/0773n4q3gfp34j5v pmid:15899779 fatcat:fmmp67iwjjgbtar7ddvheypmam