The effect of oral nutritional supplementation on selected pathology and anthropometric markers of health status in middle aged men

PS Wood, JW De Vos, CC Grant
2010 African Journal for Physical Health Education Recreation and Dance  
This study was aimed at determining whether treatment with nutritional supplementation would improve pathology measures of disease risk. A total of twenty (20) healthy males, 30-60 years of age, served as participants. Participants were randomly divided into an Active Group (AG) (n=10) and a Placebo Group (PG) (n=10). Participants took the treatment (with active or placebo ingredients) for 90 days. On day 1 and 90 th day blood samples were collected and analysed for cardiovascular disease risk
more » ... arkers (HDL, LDL, Triglycerides, total cholesterol and C reactive protein). To evaluate renal function urea, electrolytes creatinine and g GFR were analysed. White cell count and differential count were used as indicators of immune function. Vit B 12 and s-folate were also analysed. No significant differences were found between the pre-test and post-test readings in the PG, whilst the AG experienced significant differences between the pre-and posttest in sodium and s-folate readings. On sodium readings the AG presented more cases with significantly lower levels during the post-test whilst s-folate was statistically higher during the post-test. No significant changes were found in any of the other pathology disease markers. It can be concluded despite the significant improvement in folic acid and sodium level observed in the AG participants that the nutritional supplement rich in folic acid, Vit B 6 , Vit B 1 , Vit B 12, zinc, calcium, amino acid, Vit E and Vit C used for a period of 90 days has no effect on selected pathology markers of health status in middle-aged sedentary men.
doi:10.4314/ajpherd.v15i4.49551 fatcat:zi6ddjvlgjfwblbc3w4xd2y4v4