Introducti on: The metabolic syndrome (MS) is a cluster of complex interrelated risk factors for diabetes and cardiovascular disease which includes central obesity, glucose intolerance, hypertension, high triglyceride and low HDL-C. The prevalence of MS in Asian Indian is 49.2%. There is evidence of increasing prevalence of MS in the world. Therefore, we intended to fi nd the prevalence of the metabolic syndrome in the local populati on of Patan, a major urban center in Nepal. Methods : It was

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... cross-secti onal study which was carried out in one of the urban clusters (or wards) of the Lalitpur Sub-Metropolitan (or Patan) City. Measurements of waist circumference, height, weight; blood parameters like lipid profi le, fasti ng blood sugar (FBS) were done. Measurement of blood pressure was done. The prevalence of MS was obtained by using three diff erent criteria Joint Interim Statement 2009 criteria, Internati onal diabetes federati on (IDF) 2005 criteria and Nati onal cholesterol educati on program adult treatment Panel (NCEP ATP) III 2001 criteria. Results: There were 205 parti cipants among which 34.6% were male and 65.4% were female. The prevalence of MS as per the Joint Interim Statement 2009, IDF 2005 and NCEP ATP III 2001 criteria was 61.7%, 52.7% and 43.4% respecti vely. There was signifi cantly high total cholesterol (TC), triglyceride (TAG), FBS, systolic blood pressure (SBP) and diastolic blood pressure (DBP) and signifi cantly low HDL-C in the individuals with MS compared to the normal individuals. The logisti c regression revealed the increasing prevalence of MS with increasing age, BMI and positi ve family history of diabetes. Conclusions: There is high prevalence of MS in the study populati on. Age, BMI and family history of diabetes are found to be the main predictors for metabolic syndrome.