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The amount of computing resources currently available on Clouds is large and easily available with pay per use cost model. E-Science applications that need to be executed on-demand can benefit from the Cloud, because no permanent computing resources to support peak demand has to be acquired. In this paper, we present AMOS, a system that automates creation and management of temporary Grids on a Cloud to execute (parts of) application workflows. We performed experiments with AMOS and adoi:10.1109/escience.2010.15 dblp:conf/eScience/StrijkersTHGBVLM10 fatcat:76oruodzhnbzvclrkp4ueequ3m