Synthesis of some Pyrimidine-2-one and Pyrimidine-2-thione Compounds

Hiba A. Ebraheem
2013 Rafidain journal of science  
An efficient synthesis of chalcones (1-7) was achived by condensation of substituted benzaldehyde with substituted acetophenone in ethanolic sodium hydroxide (50%).The chalcones were reacted with urea and thiourea to give the pyrimidinones(8-14) and pyrimidinethiones(15-21) respectively. All the prepared compounds were confirmed by the available physical and spectral methods.
doi:10.33899/rjs.2013.67577 fatcat:3pc4zee2sfghbg36djiz2tctcy