Human prion disease is known as new variant Creutzfeldt-Jakob disease (CJD), prion protein is not virus, but a special protein which is infectious (protinactious infectious particles, PRION). Creutzfeldt-Jakob disease is a group of infectious prion protein caused by sporadic, dominantly inherited, transmissible neurodegenerative disease, which is characterized by pathologic spongy degeneration of the brain. Previously authors have published their idea in detail to prion protein disease.

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... criteria of protecting medical staff and patients for this kind of disease was illustrated. In China, many hospitals have limited equipment and lacking knowledge of rare disease. We treated a suspicious CJD patient and diagnosed with CJD after professional test. We took many measures to protect people who have direct or indirect contact with the patient and to prevent the transmission of virus. Firstly, we provide protection knowledge for health care workers and patient's families. Secondly, we made strict infection and isolation for environment and instruments. Thirdly, cut off the transmission and other factors to prevent the spread of disease. We are successfully got our goal that nobody was infected during the hospitalization. Creutzfeldt-Jakob disease has a high infection possibility, it is apparent that positive and effective protection management is needed. Health education has an important significance for preventing Creutzfeldt-Jakob disease infection. Here is report presenting how we took care of the CJD patient.