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J P P JOURNAL OF PROTEINS AND PROTEOMICS
Blue light sensors using FAD (BLUF) domains are flavin based blue light photoreceptors. The BLUF domains are often fused with various effector domains. BLUF domain coupled with adenylyl cyclase domain is known as photoactivated adenylyl cyclase (PAC). Naegleria gruberi genome database analysis revealed the presence of four PACs. Each of the photoactivated adenylyl cyclases from Naegleria gruberi (NgPACs) is composed of a BLUF domain and an adenylyl cyclase domain. Light regulated enzymaticfatcat:zznmvppeizd5bnj4553h5clyoe