GC FINGERPRINT DEVELOPMENT OF TRACHYSPERMUM AMMI LINN. AND ITS MARKETED POLYHERBAL FORMULATIONS "AJMODADI CHURNA"

Singh Nitu, Ramanjaneyulu
INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACY AND CHEMISTRY   unpublished
Most of the traditional systems of medicines are effective but they lack standardization. So there is a need to develop standardization technique. Standardization of herbal formulations is essential in order to assess the quality, purity, safety, and efficacy of drugs based on the amounts of their active principles. Ajmodadi churna contains eleven herbal ingredients in which Trachyspermum ammi is one of the main ingredient and it is used in the treatment of indigestion, constipation and to
more » ... ipation and to improve appetite. In this research paper, an attempt has been made to develop standardization method based on the Phytochemical investigation and GC fingerprinting profile of Trachyspermum ammi and its marketed polyherbal formulations, Ajmodadi churna of four different companies. The fingerprinting profile of Trachyspermum ammi is taken as a reference standard in comparing with four marketed formulations of Ajmodadi churna. The main objective of the present study was focused on identification of Trachyspermum ammi present in polyherbal formulations of Ajmodadi churna based on Phytochemical investigation and GC fingerprinting profiles.
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