More than nine million people contact the UK's ambulance services every year. NIHR-funded research is changing the way that 999 services are delivered, by identifying the best ways of treating urgent healthcare problems and providing better emergency care. This themed review brings together a range of studies, from clinical trials of new treatments to observational research on decision-making by ambulance staff. "Twenty years ago, there was little evidence in the pre-hospital setting. Seeing

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... s research makes me realise how far we have come, yet there are still many questions that remain unanswered. We have greater research engagement by ambulance staff than ever before, and this commitment will continue to drive forward research for better emergency care and improved patient outcomes."