Currently, there is no established treatment for Long COVID (LC), but epipharyngeal abrasive therapy (EAT) has been reported to be useful in cases of complicated chronic epipharyngitis. In this study, we performed EAT on LC patients with chronic epipharyngitis and investigated the effects of EAT on subjective symptoms, examination findings, and autonomic nervous system function. Methods: Epipharyngeal abrasive therapy (EAT) was performed on 31 patients with Long COVID with chronic

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... . We recorded changes in subjective symptoms using the EAT score and changes in bleeding during abrasion using the bleeding score. Heart rate variability analysis was performed before and after treatment to assess autonomic function. Results: Bleeding and EAT scores improved significantly over time (p < 0.01), but the autonomic function test did not show any significant improvement. Noting that, the EAT score improved earlier than the bleeding score did. Conclusions: Assuming that the improvement in autonomic function would take time, we consider EAT to be a useful treatment for patients with LC who have chronic epipharyngitis.