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had a significantly lower CIR than patients who received 2 mg, with P < 0.001 in both comparisons. Conclusion In this study we demonstrate that a standard (2 mg) dose of midazolam is associated with a significantly higher caecal intubation rate than lower doses. Following stratification of patients by adequacy of bowel preparation, CIR remained lower in the low dose midazolam group. Appropriate patient selection for standard dose midazolam is important to avoid respiratory and cardiovasculardoi:10.1136/gutjnl-2014-307263.303 fatcat:ggkztbun35gwbhvlzm5zbagthe