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procedures within a post treatment 180-day follow-up period was analyzed by quartile. A nested case-control study was also performed. Results: 1,259 patients were eligible for final analyses. During 3,980 person-years follow-up, 167 patients had recurrent urolithiasis needed for surgical intervention. From first to fourth quartile of drug exposure, recurrence rates were 45. 64, 47.19, 43.11, and 18.52 per 1,000 person-years. The adjusted hazard ratio was 0.46 (95% CI ¼ 0.24 to 0.89) for thedoi:10.1016/j.urols.2015.06.224 fatcat:uiohsc6q2vhnjha6lrblzp2enm