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VIIth International Congress on Thrombosis and Haemostasis
The role of trans isomers of fatty acids in the development of coronary heart disease has been questioned. Hwang and Kinsella (l) indicated that feeding of trans linoleate to rats caused decreased serum prostaglandins. We report the effect of trans isomers of oleic and linoleic acids on platelet aggregation (PA). No significant differences were observed in collagen- and ADP-induced PA in platelet rich plasma preincubated with the various fatty acids bound to albumin for 90 min. When the albumindoi:10.1055/s-0039-1684766 fatcat:4skk6wlenzgldjph6igz24uaku