Neurocognitive effects of chemotherapy in adults

Janette Vardy
2008 Australian Prescriber  
a subset of patients complain that their memory and concentration is not as sharp after receiving treatment for solid tumours. This problem persists in some patients, but there is no correlation between self-reported impairment and cognitive impairment detected on formal neuropsychological testing. Self-reported cognitive impairment is strongly associated with fatigue, anxiety and depression, but these symptoms are not correlated with objective impairment. Cross-sectional studies found that
more » ... 0% of oncology patients have impairment after chemotherapy, with prospective studies reporting that up to 30% of patients have cognitive impairment before chemotherapy. apart from the treatment of anxiety and depression, there is no proven intervention to prevent longterm impairment or to treat it once it has occurred.
doi:10.18773/austprescr.2008.012 fatcat:fp5ubl3wezbzznwhiuillhqaqm