Gut microbiome in ADHD and its relation to neural reward anticipation

Esther Aarts, Thomas H. A. Ederveen, Jilly Naaijen, Marcel P. Zwiers, Jos Boekhorst, Harro M. Timmerman, Sanne P. Smeekens, Mihai G. Netea, Jan K. Buitelaar, Barbara Franke, Sacha A. F. T. van Hijum, Alejandro Arias Vasquez (+1 others)
2017 PLoS ONE  
Microorganisms in the human intestine (i.e. the gut microbiome) have an increasingly recognized impact on human health, including brain functioning. Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder associated with abnormalities in dopamine neurotransmission and deficits in reward processing and its underlying neuro-circuitry including the ventral striatum. The microbiome might contribute to ADHD etiology via the gut-brain axis. In this pilot study, we
more » ... potential differences in the microbiome between ADHD cases and undiagnosed controls, as well as its relation to neural reward processing. OPEN ACCESS Citation: Aarts E, Ederveen THA, Naaijen J, Zwiers MP, Boekhorst J, Timmerman HM, et al. (2017) Gut microbiome in ADHD and its relation to neural reward anticipation. PLoS ONE 12(9): e0183509.
doi:10.1371/journal.pone.0183509 pmid:28863139 pmcid:PMC5581161 fatcat:uhysg2eobvdvtnfzhhbvupc4oi