Characterization of Kcnk3 -Mutated Rat, a Novel Model of Pulmonary Hypertension

Mélanie Lambert, Veronique Capuano, Angèle Boet, Laurent Tesson, Thomas Bertero, Morad K Nakhleh, Séverine Remy, Ignacio Anegon, Christine Péchoux, Aurélie Hautefort, Catherine Rücker-Martin, Boris Manoury (+7 others)
2019 Circulation Research  
Pulmonary arterial hypertension is a severe lethal cardiopulmonary disease. Loss of function mutations in KCNK3 (potassium channel subfamily K member 3) gene, which encodes an outward rectifier K+ channel, have been identified in pulmonary arterial hypertension patients.
doi:10.1161/circresaha.119.314793 pmid:31347976 fatcat:a3mbv7tunbeubirijdffbecbhi