A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit <a rel="external noopener" href="http://www.ama.ba/index.php/ama/article/download/364/pdf">the original URL</a>. The file type is <code>application/pdf</code>.
TNS1-ALK Fusion in a Recurrent, Metastatic Uterine Mesenchymal Tumor Originally Diagnosed as Leiomyosarcoma
<span title="">2019</span>
<i title="Academy of Sciences and Arts of Bosnia anad Herzegovina">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/2fccgcswnbcgfpo2pmkqcnusy4" style="color: black;">Acta Medica Academica</a>
</i>
Preserved Fulltext
We report a female patient diagnosed with a leiomyosarcoma and who harbored a druggable target as identified by comprehensive genomic profiling in the course of clinical care. The patient progressed five years after curative intent surgery and adjuvant treatment. After failure of multiple lines of chemotherapy,she was enrolled in a trial of an ALK inhibitor based on comprehensive genomic profiling (CGP) identifying an TNS1-ALK fusion. In this case, identification of the ALK kinase fusion
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5644/ama2006-124.248">doi:10.5644/ama2006-124.248</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31264439">pmid:31264439</a>
<a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/itmkrhckvbccngo5uzycjvl2by">fatcat:itmkrhckvbccngo5uzycjvl2by</a>
</span>
more »
... ed enrollment in a matched mechanism driven clinical trial after exhausting standard of care treatment options. CGP raises the possibility of uterine inflammatory myofibroblastic tumor as an alternative diagnosisto leiomyosarcoma, highlighting the complementary role of CGP beyond immunohistochemical analyses.
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200321120017/http://www.ama.ba/index.php/ama/article/download/364/pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext">
<button class="ui simple right pointing dropdown compact black labeled icon button serp-button">
<i class="icon ia-icon"></i>
Web Archive
[PDF]
<div class="menu fulltext-thumbnail">
<img src="https://blobs.fatcat.wiki/thumbnail/pdf/05/bc/05bc7d988ae663af136f40f3e49573ee614ad63f.180px.jpg" alt="fulltext thumbnail" loading="lazy">
</div>
</button>
</a>
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5644/ama2006-124.248">
<button class="ui left aligned compact blue labeled icon button serp-button">
<i class="unlock alternate icon" style="background-color: #fb971f;"></i>
Publisher / doi.org
</button>
</a>