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Heme Oxygenase-1 Deficiency Accelerates Formation of Arterial Thrombosis Through Oxidative Damage to the Endothelium, Which Is Rescued by Inhaled Carbon Monoxide
2007
Circulation Research
Preserved Fulltext
Heme oxygenase (HO)-1 (encoded by Hmox1) catalyzes the oxidative degradation of heme to biliverdin and carbon monoxide. HO-1 is induced during inflammation and oxidative stress to protect tissues from oxidative damage.
doi:10.1161/circresaha.107.158998
pmid:17885218
fatcat:dp7gstjpu5gp3losrlmdjb2ufi