Large deviations for two-scale chemical kinetic processes

Tiejun Li, Feng Lin
2017 Communications in Mathematical Sciences  
We formulate the large deviations for a class of two scale chemical kinetic processes motivated from biological applications. The result is successfully applied to treat a genetic switching model with positive feedbacks. The corresponding Hamiltonian is convex with respect to the momentum variable as a by-product of the large deviation theory. This property ensures its superiority in the rare event simulations compared with the result obtained by formal WKB asymptotics. The result is of general
more » ... interest to understand the large deviations for multiscale problems. *
doi:10.4310/cms.2017.v15.n1.a6 fatcat:5e3uf3ba2rhstc6v5vd2uykcs4