Pathophysiology of hypertension in blacks and whites. A review of the basis of racial blood pressure differences

R F Gillum
1979 Hypertension  
Differences in blood pressure between blacks and whites in the United States are now well documented. The causes of these differences remain speculative. Genetic factors, personal characteristics, renal physiology, endocrine factors, autonomic nervous system function, cardiac function and various environmental factors are examined in the present review as potential determinants of racial blood pressure differences. Racial differences in renal physiology and environmental influences such as
more » ... uences such as socioeconomic status seem to be likely candidates for important contributions to blood pressure differences. Further research aimed specifically at black-white blood pressure differences is of great importance to a fundamental understanding of the etiology and prevention of essential hypertension. (Hypertension 1: 468-475, 1979) KEY WORDS • hypertension • blood pressure • blacks • Negro • race pathophysiology • epidemiology S EVERAL decades after the advent of a reliable method for indirect measurement of blood pressure, reports of population surveys of blood pressure began to appear. The first systematic surveys were in whites only. However, in the 193O's, data began to emerge suggesting higher blood pressure levels in blacks in selected populations. 1 Yet as late as
doi:10.1161/01.hyp.1.5.468 pmid:541040 fatcat:fuu5csunj5dhddmbwpcdfv7fri