Effects of gymnemic acid on sweet taste perception in primates

D. Glaser, G. Hellekant, J.N. Brouwer, H. van der Wel
1984 Chemical Senses  
Application of gymnemic acid (GA) on the tongue depresses the taste of sucrose in man. This effect, as indicated by electrophysiological responses, has been found to be absent in three nonhuman primate species. In the present behavioral study the effect of GA on taste responses in 22 primate species, with two subspecies, and 12 human subjects has been investigated. In all the nonhuman primates studied, including the Pongidae which are closely related to man, GA did not suppress the response to
more » ... ucrose, only in man did GA have a depressing effect Abstract. Application of gymnemic acid (GA) on the tongue depresses the taste of sucrose in man. This effect, as indicated by electrophysiological responses, has been found to be absent in three nonhuman primate species. In the present behavioral study the effect of GA on taste responses in 22 primate species, with two subspecies, and 12 human subjects has been investigated. In all the nonhuman primates studied, including the Pongidae which are closely related to man, GA did not suppress the response to sucrose, only in man did GA have a depressing effect.
doi:10.1093/chemse/8.4.367 fatcat:pxd3zdpn6venbccfcgcqbejxoy