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Hybridization is frequent in many organismal groups, but its role in adaptation is poorly understood. In sunflowers, species found in the most extreme habitats are ancient hybrids, and new gene combinations generated by hybridization are speculated to have contributed to ecological divergence. This possibility was tested through phenotypic and genomic comparisons of ancient and synthetic hybrids. Most trait differences in ancient hybrids could be re-created by complementary gene action indoi:10.1126/science.1086949 pmid:12907807 fatcat:if5alkmg2rf6nkoyp26wnbnm5i