With the development of multisource satellite platforms and the deepening of remote sensing applications, the growing demand for high-spatial resolution and high-temporal resolution remote sensing images has aroused extensive interest in spatiotemporal fusion research. However, reducing the uncertainty of fusion results caused by sensor inconsistencies and input data preprocessing is one of the challenges in spatiotemporal fusion algorithms. Here, we propose a novel sensor bias correction

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... to correct the input data of the spatiotemporal fusion model through a machine learning technique learning the bias between different sensors. Taking the normalized difference vegetation index (NDVI) images with low-spatial resolution (MODIS) and high-spatial resolution (Landsat) as the basic data, we generated the neighborhood gray matrices from the MODIS image and established the image bias pairs of MODIS and Landsat. The light gradient boosting machine (LGBM) regression model was used for the nonlinear fitting of the bias pairs to correct MODIS NDVI images. For three different landscape areas with various spatial heterogeneities, the fusion of the bias-corrected MODIS NDVI and Landsat NDVI was conducted by using the spatiotemporal adaptive reflection fusion model (STARFM) and the flexible spatiotemporal data fusion method (FSDAF), respectively. The results show that the sensor bias correction method can enhance the spatially detailed information in the input data, significantly improve the accuracy and robustness of the spatiotemporal fusion technology, and extend the applicability of the spatiotemporal fusion models.