Effects of regular aerobic exercise on cardiorespiratory fitness and levels of fibrinogen, fibrin D-dimer and uric acid in healthy and inactive middle aged men

Bizheh, Jaafari
2012 Downloaded from journal.skums.ac.ir at   unpublished
Cite this article as: Bizheh N, Jaafari M. Effects of regular aerobic exercise on cardiorepiratory fitness and levels of fibrinogen, fibrin D-dimer and uric acid in healthy and inactive middle aged men. Background and aims: The aim of this study was to investigate the effects of three months regular aerobic exercises on the levels of fibrinogen, fibrin D-dimer, uric acid, white blood cells count (WBC), red blood cell distribution width (RDW), body mass index (BMI) and cardiorespiratory fitness
more » ... espiratory fitness in middle aged healthy and inactive men. Methods: To implementation of this semi-experimental research, from employees in Ferdowsi university, 21 middle aged men with available method were selected and assigned into experimental (N=11, age: 44.7±4.3 y, height: 1.73±0.04 m, weight: 81.8±9.36 kg) and control (N=10, age: 41.2±8 y, height: 1.73±0.07 m, weight: 78.2±14.8 kg) groups. The experimental group performed an aerobic exercise protocol with the intensity of 75% to 85% of their maximum heart rate for three months (three days a week). Before and after trainings, aerobic power, body composition variables and fasting levels of blood variables were measured. Results: Data analysis showed a significant elevation of RDW, aerobic power and WBC and significant reduction of BMI and uric acid in experimental group (P<0.05), but no significant change was observed in the levels of fibrinogen and fibrin D-dimer. Conclusion: Considering reduction of some inflammatory atherosclerosis risk factors, aerobic exercise may be recommended for improvement of cardiovascular health in middle aged men.
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