New possibilities of modern medical science open up prospects for instrumental and laboratory diagnostics of many pathological conditions, unknown or not previously diagnosed in the practice of an orthopedist. These include bone marrow edema. Not only orthopedic traumatologists, but also rheumatologists, neurosurgeons, general practitioners, rehabilitation therapists, morphologists, and many others today face this concept in a variety of definitions, concepts of etiology, pathogenesis, and

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... cal recommendations for treatment.The authors performed a systematic review by using four open resources: electronic scientific library (elibrary), PubMed, SciVerse (Science Direct), and Scopus.The complexity of pathology lies in the fact that in each specific case, the development of treatment tactics requires a personal interpretation of the entire variety of data obtained and a case by case approach.