TRANSMISI TRANSOVARIAL VIRUS DENGUE PADA NYAMUK AEDES SPP

Angle Sorisi, Bagian Parasitologi, Fakultas Kedokteran, Universitas Sam, Ratulangi Manado
unpublished
Dengue Hemorrhagic Fever (DHF) is one of the most serious health problems in Indonesia which often causes outbreaks with numerous deaths. The disease is transmitted by Aedes sp. females. Generally, dengue virus transmission occurs horizontally from human carriers, and the dengue viruses are passed on by their vectors through blood sucking activity. After propagation in the mosquito, the viruses are transmitted to human recipients. In addition, there is a vertical transmission (transovarial) of
more » ... engue viruses in the ova of Aedes sp. females. The viruses propagate in the ova that undergo metamorphosis to become larvae, pupae, and imagoes. The transovarial transmission of dengue viruses in its vectors in endemic areas could be a causative key which is responsible for the phenomenon of increasing cases of DHF. Any effort to prevent and control DHF requires a thorough understanding about virDen transmission, including this transovarial transmission in Aedes sp females. Abstrak: Penyakit Demam Berdarah Dengue (DBD) merupakan salah satu masalah kesehatan yang semakin serius di Indonesia dan sering menimbulkan suatu Kejadian Luar Biasa (KLB) dengan jumlah kematian tinggi. Penyakit ditularkan melalui Aedes sp. betina. Transmisi virus dengue umumnya terjadi secara horizontal, yaitu dari manusia pembawa virus dengue ke nyamuk vektor Aedes sp. melalui aktivitasnya mengisap darah Setelah mengalami propagasi dalam tubuh nyamuk, virus dengue ditularkan ke manusia penerima. Selain itu, transmisi virus dapat terjadi secara vertikal (transovarial) yaitu virus dengue dalam tubuh nyamuk vektor Aedes sp. betina ke ovum, kemudian berpropagasi dalam ovum, larva, pupa, dan imago. Transmisi transovarial virus dengue ke vektornya di daerah endemik bisa menjadi kunci penyebab yang bertanggung jawab terhadap fenomena peningkatan kasus deman berdarah dengue. Upaya pencegahan dan penanggulangan DBD memerlukan pengetahuan yang matang tentang adanya infeksi transovarial virDen pada nyamuk Aedes sp.
fatcat:5ekcwa4o3rgstowk6gaf5eikw4