SAT0198 How normal are the hands of normal controls? a study with dedicated magnetic resonance imaging

M Parodi, G Dazzi, E Silvestri, G Garlaschi, E Poggi, MA Cimmino
2001 Speaker abstracts 2001   unpublished
Results Twelve of 17 patients with BD showed findings of intestinal involvement in enteroclysis (70.58%). Disease duration and duration of intestinal involvement were 3-19 years (median 8.09 years) and 1 month-8 years (median 3.02 years) respectively. The findings were aphtous ulceration (n = 10), linear ulceration (n = 4), deep ulceration (n = 1), coarse granular pattern (n = 1), thickened folds (n = 5), wall thickening (n = 2), pseudopolypoid appereance of the ileocecal valve (n = 6), long
more » ... ment involvement (n = 1), perforation and reccurrence at the side of anastomosis after right hemicolectomy (n = 1). In 50 Crohn?s cases, disease duration were 3 months-22 years (median 4.14 years). Ten cases were in the early,11 in the intermediate and 29 in the advanced radiological stage with or without complication. Conclusion . Enteroclysis is the method of choice with a high accuracy rate (70.58%) for symptomatic patients to detect the intestinal pathology in BD. . The enteroclysis findings in BD even when longstanding were usually mild when compared to those seen in CD. The main finding in BD was superficial ulceration. Deep ulceration common in CD was seen in only one patient with BD. Background Imaging of the joints is an invaluable technique for rheumatoid arthritis (RA). Magnetic resonance imaging (MRI) is increasingly used to visualise joint lesions in RA. 1 MRI is a very sensitive technique, which is able to show subtle changes of the joints. However, little is known about MRI findings in normal subjects. Objectives Our study evaluated bone lesions, articular space and thickness of the synovial membrane in normal controls. Methods 50 hands of 25 controls (19 women) with age range 31-88 years were studied. Four subjects had slight osteoarthritis of the first carpometacarpal joint: this joint was excluded from further evaluation. MRI of the hand was performed using a 0.2T dedicated device (Artoscan, Esaote, Genova, Italy). GE T1 and STIR sequences were used on the coronal and axial planes. Evaluated lesions included a) bone oedema; b) erosions; c) tenosynovitis, and d) thickness of the synovial membrane and effusion in 6 different areas of the wrist, as well as in the MCP and PIP joints. Results Bone oedema was seen in one subject only. Bone erosions were seen in 9/25 controls (36%). They were more frequent in subjects older than 65 years (50% vs. 23%; ns). The localization of erosions in the normal hand was not different from that observed in RA. Tenosynovitis of the extensor and flexor tendons was seen in 2/25 (8%) and 4/25 (16%) of controls, respectively. It was more frequent in subjects older than 65 years (41.7% vs. 7.7%; p = 0.07). Erosions and tenosynovitis were not associated with manual labour. Joint space range was calculated in 14 different locations of the hand. No differences were found according to gender. In contrast, subjects aged more than 65 years showed an increased thickness of the synovial membrane at the radio-ulnar joint (p = 0.01) and in the
doi:10.1136/annrheumdis-2001.696 fatcat:izkkrkoqrzhkbcyufpdcksosue