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Blood pressure and the kidney cortex transcriptome response to high sodium diet challenge in female nonhuman primates
AbstractBlood pressure (BP) is influenced by genetic variation and sodium intake. Ninety percent of Americans consume more than the AHA recommended amount of sodium. Studies on the impact of genetic variation and sodium intake on BP in nonhuman primates (NHP) to date have focused on males. We hypothesized that variation in renal transcriptional networks correlate with BP response to high dietary sodium in female baboons. Sodium-naïve female baboons (n=7) were fed a low-sodium (LS) diet for 6doi:10.1101/2021.10.29.466291 fatcat:iytqx2jiznfzxle6cigyx6lb7i