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Isolated sphenoid inflammatory disease is a rare clinical condition among patients with paranasal sinus disease, reported incidence between 1%-3%. 1 The most common symptoms of isolated sphenoid inflammatory lesions are headache, ophtalmological and nasal symptoms. Delayed diagnosis may occur due to its nonspecific symptoms. 2 The disease requires appropriate and good imaging technique for diagnosis. The aim of the study to discuss different pathologies of isolated sphenoid inflammatorydoi:10.15406/joentr.2018.10.00355 fatcat:voyp74uhnnavpkwm5tldmnzzi4