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Characteristics of cell proliferation in acute leukemia
Bone marrow aspirates and venous blood samples from 26 subjects with acute leukemia in relapse and from 10 nonleukemic controls were incubated in vitro with tritiated thymidine and examined by autoradiography. Twenty leukemic patients were studied again during the course of chemotherapy. The number of labeled cells per 100 nonerythroid nucleated cells provided an estimate of the population, which was in the DNA-synthesis phase of the generative cycle. This ratio was used as an indicator of thepmid:4502172 fatcat:pilwakw3v5byhncbihpaokejte