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INFLUENCE OF MESENCHYMAL STEM CELLS DERIVED FROM BONE MARROW OF CHILDREN WITH ONCOHEMATOLOGICAL DISEASES ON PROLIFERATION AND SELF-RENEWAL OF HEMATOPOIETIC PROGENITOR CELLS IN VITRO
unpublished
Aim: To test the ability of cultured mesenchymal stem cells (MSCs) from bone marrow (BM) of children with oncohematological disea ses after chemotherapy and radiation to support proliferation and self renewal of hematopoietic cells in vitro. Methods: BM samples of 8 patients and 9 healthy childrendonors used for MSCs preparation applying techinque of expansion in vitro. CD34 + cells were isolated from BM of donors. The ability of MSCs to maintain hematopoietic stem cells (HSCs) proliferation
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