Predicting the Effect of Carotid Artery Occlusion During Carotid Endarterectomy

Dennis D. Doblar, Nataliya V. Plyushcheva, William Jordan, Holt McDowell
1998 Stroke  
and Purpose-We correlated the mean transcranial Doppler blood flow velocity (FVm) during carotid endarterectomy with the functional collateral pathway(s) documented by angiography. Methods-Three patient groups were established: group 1 was dependent on the anterior communicating artery, group 2 on the anterior communicating artery and ipsilateral posterior communicating artery, and group 3 on the ipsilateral posterior communicating artery. Continuous middle cerebral artery FVm and
more » ... m and electroencephalographic monitoring were performed in 45 patients during carotid endarterectomy. Results-Clamped FVm was lowest in group 3 at 17Ϯ9 cm/s versus 36Ϯ16 and 33Ϯ11 cm/s for groups 1 and 2 (PϽ0.01). FVm values in groups 1 and 2 were similar. There was significant cerebral arterial vasodilation in group 3 patients on the basis of a pulsatility index of 0.38Ϯ0.15. The maximum FVm after clamp release was similar among the 3 groups. Normalized blood flow velocity 1 minute before release of the clamp was increased from the minimum flow velocity after clamping only in group 1 and 2 patients. Conclusions-The ipsilateral posterior communicating artery is a minor collateral pathway during acute carotid occlusion that contributes little to the collateral flow if there is a functional anterior communicating artery. Collateral flow through the middle cerebral artery is not recruited during occlusion in group 3 patients. The reperfusion FVm transient is independent of the primary collateral pathway. Documentation of functional collateral pathways on the basis of Doppler or angiographic examination may be advantageous in future studies since it can provide the basis for comparison among studies.
doi:10.1161/01.str.29.10.2038 pmid:9756578 fatcat:egrsjhpgcjfuxnqhowxful3tjm