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Sperm membrane protein profiles of fertile and infertile men: identification and characterization of fertility-associated sperm antigen
BACKGROUND: Male infertility is the major cause of conception failure in about 25% of all infertile couples. Understanding the causes of male infertility depends to a certain extent on the proteins present on the spermatozoa. The study aim was to investigate ®rst, whether there is any difference in the expression of sperm membrane proteins between fertile and infertile males; and second, whether there is any functional signi®cance of these proteins in the spermatozoa. METHODS: Six differentdoi:10.1093/humrep/deh066 pmid:14747160 fatcat:pkuozwqqknenbd3j4oikvhuq3i