The Alteration of Life Quality Between Hormone Treatment-Receiving and Non-Receiving Early-Stage Prostate Cancer Patients Who Underwent Radiotherapy

Feryal Karaca
2018 Eastern Journal Of Medicine  
The purpose of this prospective study was to compare the life qualities of radiotherapy -receiving early-stage prostate cancer patients during their controls done prior to, at the last week of, and 3 months after, the radiotherapy procedure. Curative surgery or radiotherapy is the treatment of choice in localized prostate cancer. Androgen deprivation therapy, which is performed according to the risk groups, is effective in the downsizing of the prostate. The European Organization for Research
more » ... d Treatment of Cancer Quality of Life Questionna ire EORT-QLQ C30 is an effective means of evaluating the quality of life on the basis of the individual's physical and functional scales. 35 prostate cancer patients who had not undergone surgery and who received curative radiotherapy were included in the study. The study was performed prospectively. The life qualities and weights of prostate cancer patients were evaluated before, at the end of, and 3 months after, the radiotherapy sessions, by means of the EORTC -QLQ 30 Test. The alterations encountered in hormone-receiving patients on the basis of physical, emotional, perceptional, and social scores, in addition to fatigue, nausea, vomiting and pain evaluations, done on the basis of the EORTC -QLQ 30 measurements performed prior to, at the end of and 3 months after, the radiotherapy sessions, were found to be statistically significant (p<0.001). Patients who did not receive hormone therapy in the emotional and pain scores demonstrated statistically significant changes during the same evaluations p=0.006, and p=0.019, respectively. It was concluded at the end of the study, that radiotherapy, in general, does not impose a negative effect on the quality of life in prostate cancer patients but it does lead to changes in the general and emotional functional scor es, as well as the complaints of pain, insomnia, constipation, and diarrhea.
doi:10.5505/ejm.2018.66933 fatcat:wsd3isfflfcklams5rcbzjpa3y