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High Sensitivity CZE-ESI-MS/MS: Method Development and Applications
Proteomic studies are usually performed using LC-MS, UPLC-MS through out the past decades. However, electrophoresis has emerged as a high-resolution separation method that can be coupled to various detection method for a thorough analysis of the proteome of any biological system. The Dovichi group uses capillary zone electrophoresis (CZE) coupled to a mass spectrometry through electrospray ionization (ESI) to perform bottom-up analyses of complex proteomes. In this work, we demonstrate thedoi:10.7274/ht24wh27j0w fatcat:hc6qfaclgvgkratvodbfm55vuu