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The aim of this study was to assess the feasibility and reproducibility of semi-automatic volumetric measurement of retroperitoneal lymph node metastases in testicular cancer (TC) patients treated with chemotherapy versus the standardized manual measurements based on RECIST criteria. Methods 21 TC patients with retroperitoneal lymph node metastases of testicular cancer were studied with a CT scan of chest and abdomen before and after cisplatin based chemotherapy. Three readers, a surgicaldoi:10.1371/journal.pone.0168977 pmid:28081195 pmcid:PMC5230761 fatcat:jryxnibqkvbmjkucl5yaybgcga