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System, Charlottesville, VA 22908). COMMENT. Adolescent drivers with ADHD when treated with Concerta q.d. demonstrated less variability and performed significantly better throughout the day than when treated with immediate release MPH t.i.d. During the MPH t.i.d. treatment regimen driving performance deteriorated significantly by 8 PM., a time when adolescents are likely to be driving. Concerta-treated adolescents were less likely to brake inappropriately on the open road, their driving wasdoi:10.15844/pedneurbriefs-18-3-9 fatcat:ooxcd2d6nbg3xgqnjv47xjyzvu