System, Charlottesville, VA 22908). COMMENT. Adolescent drivers with ADHD when treated with Concerta q.d. demonstrated less variability and performed significantly better throughout the day than when treated with immediate release MPH t.i.d. During the MPH t.i.d. treatment regimen driving performance deteriorated significantly by 8 PM., a time when adolescents are likely to be driving. Concerta-treated adolescents were less likely to brake inappropriately on the open road, their driving was

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... erratic, and they were less likely to run stop signals. The participants unblinded self-appraisals correlated significantly with the objective measures of driving performance on the simulator. ADHD is not only a school-based disorder, impacting behavior and learning, but also predisposes to accidental injuries related to bicycles and motor vehicles. Treatment benefits with the various formulations of MPH, amphetamines, and Strattera should consider the impact on risk of serious accidents in addition to school performance.