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Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution
2018
Nature Communications
Detecting the genomic changes underlying phenotypic changes between species is a main goal of evolutionary biology and genomics. Evolutionary theory predicts that changes in cisregulatory elements are important for morphological changes. We combined genome sequencing, functional genomics and genome-wide comparative analyses to investigate regulatory elements in lineages that lost morphological traits. We first show that limb loss in snakes is associated with widespread divergence of limb
doi:10.1038/s41467-018-07122-z
pmid:30413698
pmcid:PMC6226452
fatcat:2nkclui35zenffzzzprr2w7kwy