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Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing
Journal of Behavioral and Brain Science
Evidence supports the involvement of oxytocin in social behavior. The oxytocin receptor gene (OXTR) has been associated with differences in social brain function and risk for autism. Motivated by recent work, we investigated the effect of variation in the common functional rs2268498 T/C polymorphism in the promoter region of OXTR on neural responses to fear expressions. 46 healthy subjects were divided into genotype groups of C carriers (n = 32) and TT homozygous (n = 14) and neural activitydoi:10.4236/jbbs.2012.21007 fatcat:qwooosmrgzabvof7n4atggboz4