Screening of breast lesions: a comparative study between mammography, B-mode ultrasonography, sonoelastography and histological results

Raquel Constantino Pardal, António Fernando Lagem Abrantes, Luís Pedro Vieira Ribeiro, Rui Pedro Pereira Almeida, Kevin Barros Azevedo, Teresa Leonor Figueiredo, Sónia Isabel Rodrigues
2013 Radiologia Brasileira  
Objective To compare the capacity of mammography, sonoelastography, B-mode ultrasonography and histological analysis to differentiate benign from malignant breast lesions. Materials and Methods A total of 12 histopathologically confirmed breast lesions were documented. The lesions were assessed by means of mammography, B-mode ultrasonography and sonoelastography, and histopathological analysis was utilized as a gold standard. Sensitivity and specificity were calculated. A receiver operating
more » ... eiver operating characteristic (ROC) curve was constructed to evaluate the diagnostic performance of the mentioned techniques. Results Sensitivity and specificity in the differentiation between benign and malignant lesions were respectively 100% and 50% for mammography, 100% and 71% for B-mode ultrasonography, and 67% and 83% for sonoelastography. The area under the ROC curve was calculated for the three imaging modalities and corresponded to 0.792 for mammography, 0.847 for B-mode ultrasonography, and 0.806 for sonoelastography. Conclusion Sonoelastography demonstrated higher specificity and lower sensitivity as compared with mammography and B-mode ultrasonography. On the other hand, B-mode ultrasonography had the largest area under the ROC curve. Sonoelastography has demonstrated to be a promising technique to detect and evaluate breast lesions, and could potentially reduce the number of unnecessary biopsies.
doi:10.1590/s0100-39842013000400007 fatcat:5jvafq375rbxtej44pz6lazczy