CLINICAL CASE OF TOCILIZUMAB THERAPY IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

E. I. Alexeeva, E. I. Alexeeva, R. V. Denisova, T. V. Sleptsova
2013 Pediatričeskaâ Farmakologiâ  
The article presents a case of successful application of a monoclonal antibodies drug to interleukin 6 receptors (tocilizumab) at severe systemic juvenile idiopathic arthritis with the development of secondary hemophagocytic syndrome. Tocilizumab treatment secured a decrease in clinical and laboratory parameters of the disease activity, life quality improvement, systemic juvenile idiopathic arthritis and hemophagocytic syndrome remission and allowed avoiding the per os prescription of glucocorticoids.
doi:10.15690/pf.v10i4.771 fatcat:xcp4qc2xqbaiteocwk73pr3wza