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Diabetes being the most common chronic metabolic disorder has a number of complications that affect various parts of the body. Epidermal growth factor (EGF) is well known for its healing capacity. In this article we review the two way relationship between diabetes and EGF, where the former needs to block the latter's secretion and reduce its expression on order to produce its notorious complications. On the contrary, the latter is capable of reversing the former's negative adverse effect ondoi:10.19056/ijmdsjssmes/2016/v5i2/100625 fatcat:njwevgzbbncgbg2cx2wgypir6m