Packaging cells for avian leukosis virus-based vectors with various host ranges

F L Cosset, C Ronfort, R M Molina, F Flamant, A Drynda, M Benchaibi, S Valsesia, V M Nigon, G Verdier
1992 Journal of Virology  
which produces avian leukosis virus gag and pol proteins, we have constructed packaging cells with subgroups B, C, and E envelope specificities. This allows us to produce helper-free avian leukosis virus particles carrying the lacZ reporter gene and the A, B, C, or E subgroup specificities. Titers of the recombinant lacZ virus are shown to be dependent upon the type of the env subgroup and the target avian cell.
doi:10.1128/jvi.66.9.5671-5676.1992 fatcat:qzvjwqlj7bff7lgmxskycr2474