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Distant metastases of differentiated thyroid cancer: diagnosis, treatment and outcome
Nuclear Medicine Review
The remarkably good prognosis and long-term survival in differentiated thyroid cancer (DTC) are significantly reduced in patients with distant metastasis (DM). Multi-site metastases are associated with a high mortality rate reaching 92% at 5 years necessitating early diagnosis and treatment. The most common site of metastases are the lungs, followed by the bone, with the former having better prognosis than the latter due to late detection. A number of factors contribute to the development of DMpmid:18228215 fatcat:tah54ykwyjf4xll5tmx7ppxr3q