Obsessive-Compulsive Disorder (OCD) is an important cause of psychiatric morbidity in India. It is often coexistent with other psychiatric disorders such as Schizophrenia. There is no study describing OCD clinical spectrum from Central India. Aims & Objectives: To determine the clinical spectrum of obsessive-compulsive symptoms/disorder, to study the type of obsessive-compulsive symptoms/disorder, and to evaluate demographic & phenomenological variables. Material & Methods: This was a

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... e observational study in a tertiary teaching hospital. All patients presenting to the outpatient clinics or admitted to the ward were evaluated for symptoms of obsessive-compulsive disorder. All these patients who were drug naïve were selected after fulfilling the inclusion and exclusion criteria. The patients were enrolled after obtaining written informed consent. The severity of OCD was assessed on YBOCS and global severity and improvement was assessed using the CGI scale at 12 weeks follow-up. Results: We evaluated 105 patients, out of whom 26 patients had OCD/S. Thus the prevalence of OCD/S in our study was 24.7%. Patients were in the age range of 19-58 years, with nearly 51.4% patients being in the age range of 19-29 years, 21.9% in the age range of 30-39 years, and 40-49 years respectively and with only 4.7% being more than 50 years. Overall male: female ratio was 1.5:1. It was seen that 50-60% of the patients had achieved some form of education and nearly more than 50% patients had achieved a secondary and higher levels of education. The mean duration of symptoms was 33.69 months. Predominantly obsessional thoughts and ruminations were in 04 (15.4%); predominantly compulsive acts in 03 (11.5%); Mixed obsessional thoughts and acts in 19 (73.1%); Other obsessive-compulsive disorders in 0 (0%); Obsessive-compulsive disorder, unspecified in 0 (0%). Mixed OCD was seen in 19 (73.0%); predominantly obsessional in 4 (15.3%) and predominantly compulsive in 3 (11.5%) patients. Types of obsessions were: Aggressive Obsessions in 0 (0%); Contamination Obsessions in 14 (53.8%); Sexual Obsessions in 04 (15.4%); Hoarding / Saving Obsessions in 01 (3.8%); Religious Obsessions in 03 (11.5%); Obsessions with Need for Symmetry or Exactness in 01 (3.8%); Somatic Obsessions in 01 (3.8%) and Miscellaneous Obsessions in 02 (7.7%) cases. Types of compulsions were: Cleaning/Washing in 14 (53.8%); Checking in 04 (15.4%); Repeating in 04 (15.4%); Counting in 02 (7.7%); Ordering/ Arranging in 01 (3.8%); Hoarding/ Collecting in 0 (0%) and Miscellaneous compulsions were seen in 01 (3.8%) patients. At the end of 3 months then a statistically significant difference was noted on the YBOCS obsession score (t=12.359, p<0.001), YBOCS compulsion score (t=9.29, p<0.001), and total YBOCS score(t=24.154, p<0.001) from the baseline scores. Conclusions: We concluded that the prevalence of OCD in the population evaluated was 24.7%. It affected young individuals with lower socioeconomic status. Majority of patients in Group A did not work and were unemployed. The majority of patients in both the groups belonged to lower socioeconomic strata. The majority of patients had mixed obsessional thought and compulsive acts pattern of OCD, followed by obsessional thoughts predominantly compulsive acts. The most common obsessions were obsessions of contamination, sexual obsession, religious obsession, savings, need for symmetry. At the end of 3 months, there was a marked reduction in obsessive-compulsive symptoms on YBOCS.