Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation

Hyun Won Shin, Hye Won Jang, Keun Sook Kim, Ji In Lee, Ji Young Park, Sun Wook Kim, Yong-Ki Min, Myung-Shik Lee, Moon-Kyu Lee, Kwang-Won Kim, Jae Hoon Chung
2009 Journal of Korean Endocrine Society  
Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation were recently reported. Presently, we evaluated the influence of dexamethasone, somatostatin, progesterone, estradiol-17-beta, forskolin and gastrin on MTC cell proliferation and calcitonin secretion. Methods: Genomic DNA was extracted and sequenced from untreated thyroid TT cells and cells
more » ... TT cells and cells treated with 10 -5~1
doi:10.3803/jkes.2009.24.2.93 fatcat:k4tfr3s5arfwjg76wn2p6h5awe