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Simple process capability analysis and quality validation of monoclonal antibody production in bench-top bioreactor
2011
African Journal of Biotechnology
The production of monoclonal antibody (MAbs) for anti-cancer by fermentation of hybridoma cell in bench-top bioreactor was investigated. The main aim of this study was to increase the percentage of cell viability and to achieve high yield of IgM. Many ways can be applied to improve the process and one of them is by choosing the correct six sigma's design of experiment (DOE). In this study, Taguchi's experimental design was applied to achieve high percentage of cell viability in the fermentation
doi:10.5897/ajb11.2760
fatcat:aqkr4tzbxzhrbp4773xnqjplqa