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The neprilysin (NEP) family of zinc metalloendopeptidases: Genomics and function
2001
Bioessays
Neprilysin (NEP), a thermolysin-like zinc metalloendopeptidase, plays an important role in turning off peptide signalling events at the cell surface. It is involved in the metabolism of a number of regulatory peptides of the mammalian nervous, cardiovascular, inflammatory and immune systems. Examples include enkephalins, tachykinins, natriuretic and chemotactic peptides. NEP is an integral plasma membrane ectopeptidase of the M13 family of zinc peptidases. Other related mammalian NEPlike
doi:10.1002/1521-1878(200103)23:3<261::aid-bies1036>3.0.co;2-k
pmid:11223883
fatcat:bck633tppbfwhc2r27n5u4k2hu