Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon's Capsule + Conjunctival Model

Rachel Gater, Tugce Ipek, Salman Sadiq, Dan Nguyen, Lynval Jones, Alicia El Haj, Ying Yang
2019 Investigative Ophthalmology and Visual Science  
Surgical techniques such as trabeculectomy aim to treat glaucoma by making an incision into the scleral tissue, to create an alternative drainage pathway for aqueous to flow into the sub-Tenon's/subconjunctival space. However, tissue fibrosis and wound healing occurring after the procedures can reduce the success rate. This study aims to investigate the synergistic effects of aqueous humor in combination with shear stress on the fibrosis response occurring in Tenon's capsule and conjunctival tissue (TCCT) after glaucoma surgery.
doi:10.1167/iovs.18-25335 pmid:30726503 fatcat:2gsrojjqxjd75etarvwygqigxi