616 without touching the sides ; at the bottom of the bottle are placed some fragments of potash which keep the air within in a dry state. When he is about to inoculate, M. Pasteur withdraws with great care the marrow from the bottle, which he passes rapidly through the flame of a spirit-lamp, already prepared, in order to destroy the germs which might have been deposited on the surface of the marrow. With a pair of scissors, which have also been heated by the flame, he cuts two or three small

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... its of the marrow of about the length of half a centimetre, which he again cuts up into small fine pieces, and which he drops into a small glass. On the table are placed small glass balloons hermetically closed by the heat of a lamp, and which have been previously filled with sterilised broth. The assistant breaks the point of a balloon, and draws up with his mouth, through a glass tube, a little of the liquid, which he drops into the glass. This broth serves as a vehicle for the rabic marrow. With a glass rod he presses and triturates the marrow in the broth; a sort of emulsion is thus formed, which, when precipitated, leaves a yellowish liquid, with which the inoculations are performed. As stated in my last, these are executed by Dr. Grancher, and the question may be asked why M. Pasteur does not do them himself. In the first place, he would not have time, as he attends to the applicants, whose names he calls out himself, and presents them for the operation. In the next place, not being a medical man, he would be guilty, according to French law, of illegal practice. The applicants are divided into groups, and as the inoculating virus becomes altered in strength daily, ' , . the new comers are first inoculated with the weakest virus, and the older ones with the fresh virus. The assistant fills the syringe, which contains a little less than a cubic centimetre, which he hands to Dr. Grancher, who performs the operation as described in my last. I may here observe that the same needle serves for several persons on the same day without undergoing any antiseptic preparation or even being wasted, which rather surprised me, particularly in these days of microbophobia. Dr. Grancher informed me that of every ten applicants for the inoculation eight belonged to the male sex. In a conversation with M. Pasteur, he told me that the subscriptions for the establishment of a suitable place for the carrying out of his method are flowing in from all quarters, and that the amount already far exceeds his expectations. At the last meeting of the Council of Public Hygiene of the department of the Seine the sum of 1360 francs was subscribed for the undertaking. M. Pasteur who was present, thanked the Council for the interest it took in the creation of an institution which is to bear his name, and added that it would find itself thus associated with a work which will perhaps become something more than an institution for anti-rabic inoculation, and which may form a centre for the study of virulent and infectious maladies. M. Pasteur is a man of ordinary size, about sixty years of age, rather thick-set, and somewhat brusque in his manner. About ten years ago he had an attack of apoplexy, which resulted in hemiplegia of the left side, from which, however, he has in a great measure recovered, and he seems not to have lost any of his former energy and intelligence. One of the Russian patients who was bitten by a mad wolf, and who was sent to the Hotel Dieu owing to the severity of his wounds, died on Monday at that hospital from hydrophobia, the symptoms of which manifested themselves on the previous Saturday, after the eighth inoculation-that is to say, when, according to M. Pasteur's method, the treatment had not been completed. Dr. Triboulet died suddenly on Sunday night, the 21st inst. He took his degree in 1853, and was at his death physician to the Trousseau Hospital. Pa.ris, March 23rd. WE deeply regret to announce the death of this esteemed and well-known member of the profession, which took place at his residence in Portsdown-road, Maida-hill, on the 20th inst. To many of his friends the news came with a shock of surprise, for it was not widely known that his health had been broken for some months past. The first symptoms of his ailment were manifested by a syncopal attack which occurred after speaking by request at the soiree held at the Middlesex Hospital last summer. It appeared that he was suffering from aortic disease with cardiac hypertrophy, and, notwithstanding cessation of work and enforced quietude, he became subject to anginal' attacks and cardiac dyspnœa. He died in one of these paroxysms. Dr. Cobbold was one of the well-known family of that name in Suffolk. He went to Edinburgh to study medicine, and was a fellow-student and friend of several distinguished men there. He was a devoted pupil of John Goodsir and Edward Forbes. In 1851 he took his M.D. degree, and was, with Charles llurchison, Burdon Sanderson, and four others, a gold medalist of his year. He became subsequently Curator of the Anatomical Museum in the University, and was elected Senior President of the Royal Medical Society in . 1851-52, Dr. Dobie of Chester being junior president the same year. He remained for some years in Edinburgh working diligently at comparative anatomy under Goodsir. Subsequently he came to London, and was appointed Lecturer on Botany, Zoology, and Comparative Anatomy at the Middlesex Hospital School. For some time he lectured there on Parasitic Diseases. He was also lecturer at the Veterinary College. lie did not practise for some years after settling in London, and about twenty years ago he devoted himself to a limited sphere of work as a consultant in cases of parasitic disease, helminthology being a very special and favourite line of pursuit with him. He was without doubt one of the first British authorities on this subject, and made several original and valuable investigations in it, many of the results of which were from time to time contributed to our columns. He was elected into the Royal Society about 1865. His work was always carefully done, and pursued with persistency and enthusiasm. He was clear and dogmatic as a teacher, and had always the courage of his opinions. The social side of his character was well marked. He was kind and affectionate in disposition, and thus won and kept many friendships. He was devoted to music, and possessed a remarkable voice, a high pure alto, which none who ever heard it can forget. At the dinner of the Edinburgh Club, which he regularly attended, he was often a contributor to the subsequent musical entertainment. He published several works on the Entozoa, one of which is a classical treatise on the subject. Many foreign scientific societies enrolled him as honorary and corresponding member.